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Coeliac disease

Morbus coeliacus · Celiakie

What it is

Gluten triggers an immune attack that flattens the intestinal villi.

Symptoms & signs

  • Diarrhoea
  • bloating
  • weight loss
  • iron deficiency
  • mouth ulcers
  • itchy rash (dermatitis herpetiformis)
  • often silent

🚩 Get help if…

  • see a doctor soon Weight loss or a child not growing
  • see a doctor soon Symptoms continuing despite a strict gluten-free diet
  • see a doctor soon Blood in the stool or difficulty swallowing
  • see a doctor soon Severe tiredness or breathlessness (anaemia)

Where it strikes

Medical treatment

  • Strict lifelong gluten-free diet
  • dietitian input
  • check bone density
  • correct iron, B12, folate, vitamin D

Natural & lifestyle

  • Gluten-free diet is the treatment
  • oat caution
  • label literacy
  • nutrient repletion

Emerging & experimental

  • Glutenase enzymes (latiglutenase)
  • TG2 inhibitors (ZED1227)
  • Nexvax2 vaccine (stopped for lack of effect)
  • hookworm immunomodulation

Alternative, off-label & anecdotal

Approaches used outside the guidelines, with what their supporters report and what testing has found so far.

  • Over-the-counter 'gluten-digesting' enzymes (DPP-IV) — trials show they do not protect against gluten not confirmed in trials
  • Probiotics (Bifidobacterium) — small trials, fewer symptoms early / small studies
  • Gut-healing protocols (bone broth, L-glutamine) — popular; untested in coeliac disease anecdotal / traditional

ICD codes