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Deep vein thrombosis

Thrombosis venosa profunda · Hluboká žilní trombóza

What it is

A clot forms in a deep leg vein; the danger is it travelling to the lungs.

Symptoms & signs

  • Calf swelling
  • warmth
  • redness
  • tenderness
  • one leg noticeably bigger

🚩 Get help if…

  • call 112 / 911 now Sudden breathlessness or chest pain on breathing in
  • call 112 / 911 now Coughing up blood or fainting
  • see a doctor soon Swollen, painful, warm calf or thigh on one side
  • see a doctor soon Leg swelling after surgery, a long trip or in pregnancy

Where it strikes

Medical treatment

  • DOAC anticoagulation 3–6 months
  • compression stockings
  • catheter thrombolysis for massive clots
  • IVC filter if anticoagulation impossible

Natural & lifestyle

  • Move every hour on long journeys
  • hydration
  • calf exercises
  • compression on flights
  • weight management

Emerging & experimental

  • Factor XI inhibitors (abelacimab) with less bleeding
  • AI risk scores

Alternative, off-label & anecdotal

Approaches used outside the guidelines, with what their supporters report and what testing has found so far.

  • Nattokinase — lab and small human studies show clot-dissolving activity; never tested against real clots, and a bleeding risk with anticoagulants early / small studies
  • Pycnogenol on long flights — small trials report fewer clots; their quality is questioned early / small studies
  • Ginger and turmeric as blood thinners — traditional; untested, and risky with anticoagulants anecdotal / traditional

ICD codes