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Eosinophilic oesophagitis

Oesophagitis eosinophilica · Eozinofilní ezofagitida

What it is

An allergic inflammation of the gullet — often to milk, wheat or egg — that stiffens it so food gets stuck.

Symptoms & signs

  • Food sticking (often meat or bread)
  • food impaction needing endoscopy
  • heartburn that antacids don't help
  • feeding problems and vomiting in children

🚩 Get help if…

  • call 112 / 911 now Food stuck with drooling and unable to swallow saliva
  • call 112 / 911 now Chest pain or vomiting blood after food got stuck
  • see a doctor soon Food sticking again and again
  • see a doctor soon A child who refuses food or fails to grow

Where it strikes

Medical treatment

  • High-dose PPI
  • swallowed budesonide (Jorveza)
  • dupilumab
  • elimination diets (milk first, or 2–4–6 foods)
  • dilatation of narrowings

Natural & lifestyle

  • Find and avoid trigger foods with a dietitian
  • chew well, cut food small
  • treat other allergies

Emerging & experimental

  • Anti-IL-13 and anti-IL-5 biologics
  • cendakimab
  • oral immunotherapy

Alternative, off-label & anecdotal

Approaches used outside the guidelines, with what their supporters report and what testing has found so far.

  • Probiotics — animal and small human studies early / small studies
  • Vitamin D — low levels are linked; untested as treatment early / small studies
  • Slippery elm and aloe to 'coat' the gullet — anecdotal anecdotal / traditional

ICD codes