Japanese encephalitis
Encephalitis japonica · Japonská encefalitida
What it is
A mosquito-borne flavivirus of rural Asia, carried by pigs and wading birds; fewer than 1 in 100 infected fall ill, but a fifth to a third of those with encephalitis die and up to half of survivors keep lasting damage.
Symptoms & signs
- Fever, headache and vomiting
- confusion and drowsiness
- seizures, especially in children
- stiff, mask-like face, tremor (parkinsonism)
- paralysis
- coma
🚩 Get help if…
- call 112 / 911 now Confusion, drowsiness or odd behaviour with fever
- call 112 / 911 now Fits, stiff neck or weakness with fever
- call 112 / 911 now Shaking, stiff face or trouble speaking
- see a doctor soon Fever within 2 weeks of rural Asia
Where it strikes
Medical treatment
- Antibody test on spinal fluid
- supportive and intensive care: seizures, brain swelling, breathing
- no antiviral works
- Vaccination (inactivated, live or chimeric) for residents and longer-stay travellers trials support
Natural & lifestyle
- Nets and repellent at dusk
- pig farms kept away from homes
Emerging & experimental
- Ribavirin and interferon alfa — trials in India and Vietnam: no benefit not confirmed in trials
- minocycline — a small trial without clear benefit
- monoclonal antibodies
Alternative, off-label & anecdotal
Approaches used outside the guidelines, with what their supporters report and what testing has found so far.
- Traditional Chinese herbal fever formulas — used in China; untested against the virus anecdotal / traditional
- Homeopathic 'prevention' handed out in parts of India — no controlled evidence anecdotal / traditional
ICD codes
- ICD-10 A83.0
- ICD-11 1C85 Japanese encephalitis