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Lymphoma (Hodgkin & non-Hodgkin)

Lymphoma (morbus Hodgkin et lymphomata non-Hodgkin) · Lymfom (Hodgkinův a non-Hodgkinův)

What it is

Cancer of lymphocytes living in nodes and lymphoid tissue.

Symptoms & signs

  • Painless rubbery node swelling
  • night sweats
  • unexplained fever
  • weight loss over 10%
  • itching
  • alcohol-induced node pain in Hodgkin

🚩 Get help if…

  • call 112 / 911 now Fever over 38 °C during treatment
  • call 112 / 911 now Swelling of face and neck with breathlessness
  • see a doctor soon A painless lump in the neck, armpit or groin for over 3 weeks
  • see a doctor soon Drenching night sweats, fever or weight loss

Where it strikes

Medical treatment

  • ABVD or BrECADD chemotherapy for Hodgkin
  • R-CHOP for diffuse large B-cell
  • radiotherapy
  • CAR-T for relapse
  • PET-guided de-escalation
  • Bispecific antibodies (glofitamab, mosunetuzumab) for relapsed disease — approved 2022–23
  • CAR-T in second line for early-relapsing large B-cell lymphoma — approved 2022

Natural & lifestyle

  • Vaccination before treatment
  • fertility preservation counselling
  • exercise during chemotherapy
  • nutrition

Emerging & experimental

  • CtDNA-guided response adaptation

Alternative, off-label & anecdotal

Approaches used outside the guidelines, with what their supporters report and what testing has found so far.

  • Green tea extract (EGCG) in early lymphocytic disease — small trials lowered counts early / small studies
  • Essiac tea — popular herbal cancer tea; untested anecdotal / traditional

ICD codes