Infectious mononucleosis
Mononucleosis infectiosa · Infekční mononukleóza
What it is
Epstein-Barr virus, spread by saliva; teenagers and young adults hit hardest.
Symptoms & signs
- Severe sore throat
- huge tonsils
- swollen neck nodes
- profound fatigue for weeks
- fever
- enlarged spleen
- rash if given amoxicillin
🚩 Get help if…
- call 112 / 911 now Trouble breathing or swallowing saliva
- call 112 / 911 now Sudden sharp pain in the upper left belly
- see a doctor soon Yellow skin or eyes
- see a doctor soon Unable to drink enough fluids
Where it strikes
Medical treatment
- Supportive care
- fluids and analgesia
- steroids only for airway compromise
- avoid contact sport 4–6 weeks (splenic rupture risk)
Natural & lifestyle
- Rest and gradual return
- hydration
- salt-water gargles
- no alcohol while liver enzymes are raised
Emerging & experimental
- EBV vaccines in trials
- EBV link to MS driving new prevention research
Alternative, off-label & anecdotal
Approaches used outside the guidelines, with what their supporters report and what testing has found so far.
- Valaciclovir — small trials shortened symptoms early / small studies
- Echinacea and elderberry — untested for glandular fever anecdotal / traditional
ICD codes
- ICD-10 B27.0
- ICD-11 1D81.0 Mononucleosis due to Epstein-Barr virus