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Mpox (monkeypox)

Mpox (variola simiarum) · Mpox (opičí neštovice)

What it is

A pox virus related to smallpox, spread by close contact; the 2022 outbreak spread mainly through sex, with painful genital and body lesions.

Symptoms & signs

  • Fever, headache, swollen glands
  • rash turning to fluid-filled, then crusted spots
  • painful genital or anal sores
  • mouth sores

🚩 Get help if…

  • call 112 / 911 now Painful red eye or blurred sight
  • call 112 / 911 now Breathless or confused
  • see a doctor soon Sores in the mouth or throat so you cannot eat or drink
  • see a doctor soon Severe pain in the back passage or unable to pass urine

Where it strikes

Medical treatment

  • PCR swab trials support
  • Supportive care and pain relief trials support
  • Isolation until the lesions heal trials support
  • Tecovirimat — randomised trials (PALM007 in the Congo, STOMP) found no faster healing than placebo not confirmed in trials
  • MVA-BN vaccination for those at risk — good protection in observational data, no randomised outcome trial mixed evidence

Natural & lifestyle

  • Avoiding close contact with the lesions trials support
  • Vaccination if at risk, weighed as above mixed evidence

Emerging & experimental

  • Brincidofovir
  • mRNA vaccines

Alternative, off-label & anecdotal

Approaches used outside the guidelines, with what their supporters report and what testing has found so far.

  • Oatmeal baths and zinc paste for itchy sores — soothing anecdotal / traditional
  • Vitamin D and zinc — support immunity; untested here early / small studies
  • Ivermectin — no activity against pox viruses shown anecdotal / traditional

ICD codes