Anatom3DPaget's disease of bone
Osteitis deformans (morbus Paget) · Pagetova kostní choroba
What it is
Bone remodelling runs wild; new bone is bigger but weaker.
Symptoms & signs
- Bone pain
- deformity (bowed legs, enlarged skull)
- hearing loss
- fractures
- often found on X-ray by chance
🚩 Get help if…
- see a doctor soon New or fast-worsening bone pain or swelling in one spot
- see a doctor soon Sudden severe bone pain after a minor knock
- see a doctor soon Hearing loss or headaches with a growing skull
- see a doctor soon Numbness or weakness in the legs
Where it strikes
- Skeleton
- Vertebral bodies
- Femur
Medical treatment
- Single-dose IV zoledronic acid
- calcium and vitamin D
- orthopaedic surgery for deformity
- hearing assessment
Natural & lifestyle
- Vitamin D and calcium sufficiency
- weight-bearing exercise within limits
- fall prevention
Emerging & experimental
- Long-interval bisphosphonate dosing
- genetic screening in families (SQSTM1)
Alternative, off-label & anecdotal
Approaches used outside the guidelines, with what their supporters report and what testing has found so far.
- Calcium and vitamin D alone — support treatment but do not control the disease anecdotal / traditional
- Herbal bone formulas — untested anecdotal / traditional
ICD codes
- ICD-10 M88.9
- ICD-11 FB85.Z Paget disease of bone, unspecified