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Pituitary adenoma

Adenoma hypophysis · Adenom hypofýzy

What it is

A benign gland tumour that either oversecretes a hormone or presses on the optic nerves.

Symptoms & signs

  • Tunnel vision (bitemporal hemianopia)
  • headache
  • milk production
  • absent periods
  • acromegaly features
  • erectile dysfunction

🚩 Get help if…

  • call 112 / 911 now Sudden severe headache with vomiting, double vision or a drooping eyelid
  • see a doctor soon Losing the outer edges of vision, bumping into things
  • see a doctor soon Milky discharge from the nipples, or periods stopping
  • see a doctor soon Great thirst, passing lots of pale urine

Where it strikes

Medical treatment

  • Cabergoline for prolactinoma
  • transsphenoidal surgery
  • somatostatin analogues for acromegaly
  • radiotherapy
  • hormone replacement afterwards
  • pasireotide for Cushing's disease and acromegaly — approved (EMA, FDA) since 2012; raises blood sugar

Natural & lifestyle

  • Visual field monitoring
  • hormone replacement adherence
  • bone health

Emerging & experimental

  • Endoscopic extended approaches
  • temozolomide for aggressive adenomas

Alternative, off-label & anecdotal

Approaches used outside the guidelines, with what their supporters report and what testing has found so far.

  • Chasteberry (Vitex agnus-castus) — lowers prolactin in small studies; not a tumour treatment early / small studies
  • Herbal or dietary 'tumour shrinking' — none shown to work anecdotal / traditional

ICD codes