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Sarcoidosis

Sarcoidosis · Sarkoidóza

What it is

Granulomas form for no known reason, usually in lungs and lymph nodes.

Symptoms & signs

  • Dry cough
  • breathlessness
  • fatigue
  • painful shins (erythema nodosum)
  • eye inflammation
  • often symptomless

🚩 Get help if…

  • call 112 / 911 now Fainting, or a very slow or irregular heartbeat
  • see a doctor soon Painful red eye or blurred vision
  • see a doctor soon Breathlessness getting worse
  • see a doctor soon Great thirst, constipation or passing lots of urine

Where it strikes

Medical treatment

  • Observation if mild
  • prednisolone
  • methotrexate
  • infliximab
  • treat organ-threatening disease

Natural & lifestyle

  • Vitamin D caution (can raise calcium)
  • exercise
  • smoking cessation

Emerging & experimental

  • JAK inhibitors
  • Efzofitimod — missed its phase 3 primary endpoint not confirmed in trials

Alternative, off-label & anecdotal

Approaches used outside the guidelines, with what their supporters report and what testing has found so far.

  • CLEAR antibiotics (levofloxacin, ethambutol, azithromycin, rifampicin) — based on a mycobacterial theory; a small trial improved lung function early / small studies
  • Nicotine patches — a small trial improved lung function early / small studies
  • Anti-inflammatory diet and curcumin — patients report benefit; not tested anecdotal / traditional

ICD codes