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Sjögren's disease

Syndroma Sjögren · Sjögrenův syndrom

What it is

The immune system attacks the glands that make tears and saliva.

Symptoms & signs

  • Dry gritty eyes
  • dry mouth and dental decay
  • fatigue
  • joint pain
  • swollen parotid glands
  • vaginal dryness

🚩 Get help if…

  • see a doctor soon A salivary gland lump that stays or grows
  • see a doctor soon Swollen glands in the neck, night sweats or weight loss
  • see a doctor soon Numbness, tingling or weakness in hands or feet
  • see a doctor soon Painful red eye or blurred vision that does not clear

Where it strikes

Medical treatment

  • Artificial tears and saliva
  • pilocarpine
  • hydroxychloroquine for joints
  • dental prevention
  • treat lymphoma risk with surveillance

Natural & lifestyle

  • Frequent sips of water
  • sugar-free gum
  • humidifier
  • meticulous dental care
  • omega-3

Emerging & experimental

  • Iscalimab and other CD40-targeted trials
  • nipocalimab

Alternative, off-label & anecdotal

Approaches used outside the guidelines, with what their supporters report and what testing has found so far.

  • Acupuncture — small trials improved dry mouth early / small studies
  • Sea-buckthorn oil — a small trial eased dry eyes early / small studies
  • Xylitol mouth sprays and gels — small studies early / small studies

ICD codes