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Stomach cancer

Carcinoma ventriculi · Rakovina žaludku

What it is

Usually the end of a long road that began with H. pylori.

Symptoms & signs

  • Vague indigestion
  • early fullness
  • weight loss
  • vomiting
  • black stools
  • anaemia

🚩 Get help if…

  • call 112 / 911 now Vomiting blood or black tarry stools
  • see a doctor soon Weight loss with upper belly pain or indigestion
  • see a doctor soon Feeling full after a few bites or persistent vomiting
  • see a doctor soon Tiredness or breathlessness (anaemia) or a lump in the upper belly

Where it strikes

Medical treatment

  • Gastrectomy
  • perioperative chemotherapy (FLOT)
  • trastuzumab if HER2 positive
  • immunotherapy
  • H. pylori eradication as prevention
  • zolbetuximab for claudin-18.2-positive, HER2-negative advanced cancer — approved 2024 (EMA, FDA); nausea and vomiting are common

Natural & lifestyle

  • H. pylori testing
  • less salted and smoked food
  • more fruit and vegetables
  • stop smoking

Emerging & experimental

  • CAR-T against CLDN18.2
  • endoscopic screening programmes

Alternative, off-label & anecdotal

Approaches used outside the guidelines, with what their supporters report and what testing has found so far.

  • Garlic and vitamin supplements — a single large trial (Shandong) found fewer stomach-cancer deaths after 22 years mixed evidence
  • PSK (polysaccharide from a mushroom) with chemotherapy — used in Japan; modest survival gain in trials mixed evidence

ICD codes