Takayasu arteritis
Arteritis Takayasu · Takayasuova arteritida
What it is
Inflammation of the aorta and its main branches, mostly in young women, that narrows them — the 'pulseless disease'.
Symptoms & signs
- Tiredness, fever and weight loss
- arm pain on use
- weak or absent pulses, unequal blood pressures
- dizziness and fainting
- high blood pressure
🚩 Get help if…
- call 112 / 911 now Chest pain, sudden breathlessness or fainting
- call 112 / 911 now Face drooping, arm weakness or slurred speech
- call 112 / 911 now Sudden loss of vision
- see a doctor soon Arm pain or tiredness when using it, or a weak pulse at the wrist
Where it strikes
Medical treatment
- CT or MR angiography and PET
- steroids
- methotrexate or tocilizumab
- TNF blockers
- bypass or angioplasty for fixed narrowings
Natural & lifestyle
- No smoking
- bone care on steroids
- exercise within limits
Emerging & experimental
- JAK inhibitors (upadacitinib)
- ustekinumab
Alternative, off-label & anecdotal
Approaches used outside the guidelines, with what their supporters report and what testing has found so far.
- Curcumin — lab studies on vessel inflammation early / small studies
- Vitamin D — low levels are common early / small studies
- Anti-inflammatory diets — anecdotal anecdotal / traditional
ICD codes
- ICD-10 M31.4
- ICD-11 4A44.1 Aortic arch syndrome