Type 1 diabetes
Diabetes mellitus typus 1 · Diabetes 1. typu
What it is
The immune system destroys insulin-making beta cells; insulin becomes mandatory.
Symptoms & signs
- Rapid weight loss
- extreme thirst
- frequent urination
- fatigue
- fruity breath and vomiting in ketoacidosis
🚩 Get help if…
- call 112 / 911 now Vomiting, tummy pain, deep fast breathing or fruity breath
- call 112 / 911 now A hypo that doesn't respond to sugar, or too drowsy to swallow
- see a doctor soon Ketones 1.5 mmol/l or higher, or sugar staying above 15 mmol/l
- see a doctor soon A foot sore, or a sudden change in vision
Where it strikes
- Islets of Langerhans
- Pancreas
- Endocrine glands
Medical treatment
- Basal-bolus insulin or pump
- continuous glucose monitoring
- hybrid closed-loop systems
- carbohydrate counting
- ketoacidosis protocols
- teplizumab — FDA-approved 2022; delays onset in at-risk relatives by about two years
Natural & lifestyle
- Carb counting skills
- exercise with glucose planning
- hypo preparedness
- structured education (DAFNE)
Emerging & experimental
- Stem-cell-derived islets
- immunotherapy combinations
- fully closed-loop 'artificial pancreas'
Alternative, off-label & anecdotal
Approaches used outside the guidelines, with what their supporters report and what testing has found so far.
- BCG vaccination (Faustman) — a small study reported lower HbA1c years later; a larger trial did not confirm it mixed evidence
- Vitamin D and omega-3 soon after diagnosis — observational data and small trials of preserved insulin production early / small studies
- Very-low-carbohydrate diet (Bernstein method) — patients report steadier glucose; small studies; watch for lows and ketosis early / small studies
- Herbal 'cures' that promise to replace insulin — none work; stopping insulin leads to ketoacidosis and death anecdotal / traditional
ICD codes
- ICD-10 E10
- ICD-11 5A10 Type 1 diabetes mellitus