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Type 1 diabetes

Diabetes mellitus typus 1 · Diabetes 1. typu

What it is

The immune system destroys insulin-making beta cells; insulin becomes mandatory.

Symptoms & signs

  • Rapid weight loss
  • extreme thirst
  • frequent urination
  • fatigue
  • fruity breath and vomiting in ketoacidosis

🚩 Get help if…

  • call 112 / 911 now Vomiting, tummy pain, deep fast breathing or fruity breath
  • call 112 / 911 now A hypo that doesn't respond to sugar, or too drowsy to swallow
  • see a doctor soon Ketones 1.5 mmol/l or higher, or sugar staying above 15 mmol/l
  • see a doctor soon A foot sore, or a sudden change in vision

Where it strikes

Medical treatment

  • Basal-bolus insulin or pump
  • continuous glucose monitoring
  • hybrid closed-loop systems
  • carbohydrate counting
  • ketoacidosis protocols
  • teplizumab — FDA-approved 2022; delays onset in at-risk relatives by about two years

Natural & lifestyle

  • Carb counting skills
  • exercise with glucose planning
  • hypo preparedness
  • structured education (DAFNE)

Emerging & experimental

  • Stem-cell-derived islets
  • immunotherapy combinations
  • fully closed-loop 'artificial pancreas'

Alternative, off-label & anecdotal

Approaches used outside the guidelines, with what their supporters report and what testing has found so far.

  • BCG vaccination (Faustman) — a small study reported lower HbA1c years later; a larger trial did not confirm it mixed evidence
  • Vitamin D and omega-3 soon after diagnosis — observational data and small trials of preserved insulin production early / small studies
  • Very-low-carbohydrate diet (Bernstein method) — patients report steadier glucose; small studies; watch for lows and ketosis early / small studies
  • Herbal 'cures' that promise to replace insulin — none work; stopping insulin leads to ketoacidosis and death anecdotal / traditional

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