Vasculitis (GCA & others)
Vasculitis · Vaskulitida (obrovskobuněčná arteritida a další)
What it is
Immune attack on vessel walls; giant cell arteritis can blind within days.
Symptoms & signs
- Temple headache
- scalp tenderness
- jaw ache on chewing
- sudden vision loss
- fever
- weight loss
🚩 Get help if…
- call 112 / 911 now Sudden loss or blurring of vision in one eye
- call 112 / 911 now Coughing up blood or breathlessness
- see a doctor soon New temple headache or jaw pain on chewing after 50
- see a doctor soon Purple spots on the legs, blood in urine or less urine
Where it strikes
- Heart & arteries
- External carotid artery
- Aorta
Medical treatment
- Immediate high-dose steroids for GCA
- tocilizumab
- methotrexate
- rituximab for ANCA vasculitis
- cyclophosphamide in severe cases
- avacopan for ANCA vasculitis — approved (FDA 2021, EMA 2022)
Natural & lifestyle
- Bone protection while on steroids
- calcium and vitamin D
- infection precautions
Emerging & experimental
- IL-6 and JAK inhibitors
- PET-guided monitoring
Alternative, off-label & anecdotal
Approaches used outside the guidelines, with what their supporters report and what testing has found so far.
- Curcumin and fish oil as steroid-sparing — small studies only early / small studies
- Anti-inflammatory diet — patients report benefit; untested anecdotal / traditional
ICD codes
- ICD-10 I77.6
- ICD-11 4A44.Z Vasculitis, unspecified