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Aspergillosis

Aspergillosis · Aspergilóza

What it is

A mould everyone breathes that harms only some: allergic asthma flares, fungus balls in old lung cavities, or invasive infection when immunity is down.

Symptoms & signs

  • Worsening asthma with brown mucus plugs (allergic form)
  • coughing blood (fungus ball)
  • fever and chest pain (invasive form)
  • breathlessness
  • blocked sinus

🚩 Get help if…

  • call 112 / 911 now Coughing up more than a spoonful of blood
  • call 112 / 911 now Fever and cough with weak immunity (chemotherapy, transplant)
  • see a doctor soon Asthma that keeps getting worse despite treatment
  • see a doctor soon Brown plugs coughed up, weight loss or night sweats

Where it strikes

Medical treatment

  • CT, blood and sputum tests
  • voriconazole or isavuconazole
  • itraconazole and steroids for the allergic form
  • surgery for fungus balls
  • less immunosuppression where possible

Natural & lifestyle

  • Avoid compost and building dust when immunosuppressed
  • HEPA-filtered air in hospital

Emerging & experimental

  • Olorofim and fosmanogepix
  • inhaled antifungals

Alternative, off-label & anecdotal

Approaches used outside the guidelines, with what their supporters report and what testing has found so far.

  • A mould-free home — less exposure helps the allergic form early / small studies
  • Oregano oil — antifungal in the lab; untested here anecdotal / traditional
  • Vitamin D — low levels linked to the allergic form early / small studies

ICD codes