Dry eye disease
Keratoconjunctivitis sicca · Syndrom suchého oka
What it is
Tears evaporate too fast or aren't made in enough quantity.
Symptoms & signs
- Gritty burning eyes
- watering paradoxically
- blurred vision that clears on blinking
- light sensitivity
- screen-related worsening
🚩 Get help if…
- see a doctor soon Painful red eye with light sensitivity
- see a doctor soon Blurred vision that doesn't clear with blinking
- see a doctor soon Dry mouth and joint pain too (Sjögren's)
- see a doctor soon Eyelids that don't close fully
Where it strikes
Medical treatment
- Preservative-free artificial tears
- lipid-based drops
- ciclosporin or lifitegrast
- punctal plugs
- treat blepharitis
- varenicline nasal spray (Tyrvaya) — FDA-approved 2021
- perfluorohexyloctane drops (Miebo) — FDA-approved 2023; sold as a medical device in the EU
Natural & lifestyle
- 20-20-20 screen rule
- warm compresses and lid hygiene
- omega-3 — no benefit in the large DREAM trial not confirmed in trials
- humidifier
- reduce fan and air-con exposure
- hydration
Emerging & experimental
- Intense pulsed light for meibomian glands
Alternative, off-label & anecdotal
Approaches used outside the guidelines, with what their supporters report and what testing has found so far.
- Omega-3 — the large DREAM trial found no benefit not confirmed in trials
- Manuka honey eye drops — small trials early / small studies
- Sea-buckthorn oil capsules — a trial reduced symptoms early / small studies
ICD codes
- ICD-10 H04.1
- ICD-11 9A79 Keratoconjunctivitis sicca