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Long QT syndrome

Syndroma QT prolongati · Syndrom dlouhého QT

What it is

An ion-channel fault stretches repolarisation and can trigger fatal rhythms.

Symptoms & signs

  • Fainting with exercise or startle
  • seizures
  • palpitations
  • sudden death in the young
  • family history

🚩 Get help if…

  • call 112 / 911 now Fainting or a fit during exercise, fright or a sudden noise
  • call 112 / 911 now Collapse with no breathing or pulse
  • see a doctor soon Palpitations or near-fainting
  • see a doctor soon Diarrhoea, vomiting or a new medicine with known long QT

Where it strikes

Medical treatment

  • Beta blockers (nadolol)
  • avoid QT-prolonging drugs
  • ICD in high risk
  • left cardiac sympathetic denervation

Natural & lifestyle

  • Avoid swimming alone or loud alarms in LQT1/2
  • electrolyte repletion
  • family screening

Emerging & experimental

  • Gene-specific therapy
  • mexiletine for LQT3

Alternative, off-label & anecdotal

Approaches used outside the guidelines, with what their supporters report and what testing has found so far.

  • Potassium- and magnesium-rich diet — sensible support for repolarisation; untested as treatment anecdotal / traditional
  • Mexiletine and ranolazine in specific gene types — small studies early / small studies

ICD codes