Long QT syndrome
Syndroma QT prolongati · Syndrom dlouhého QT
What it is
An ion-channel fault stretches repolarisation and can trigger fatal rhythms.
Symptoms & signs
- Fainting with exercise or startle
- seizures
- palpitations
- sudden death in the young
- family history
🚩 Get help if…
- call 112 / 911 now Fainting or a fit during exercise, fright or a sudden noise
- call 112 / 911 now Collapse with no breathing or pulse
- see a doctor soon Palpitations or near-fainting
- see a doctor soon Diarrhoea, vomiting or a new medicine with known long QT
Where it strikes
Medical treatment
- Beta blockers (nadolol)
- avoid QT-prolonging drugs
- ICD in high risk
- left cardiac sympathetic denervation
Natural & lifestyle
- Avoid swimming alone or loud alarms in LQT1/2
- electrolyte repletion
- family screening
Emerging & experimental
- Gene-specific therapy
- mexiletine for LQT3
Alternative, off-label & anecdotal
Approaches used outside the guidelines, with what their supporters report and what testing has found so far.
- Potassium- and magnesium-rich diet — sensible support for repolarisation; untested as treatment anecdotal / traditional
- Mexiletine and ranolazine in specific gene types — small studies early / small studies
ICD codes
- ICD-10 I45.8
- ICD-11 BC65.0 Long QT syndrome