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Male breast cancer

Carcinoma mammae virilis · Rakovina prsu u mužů

male only

What it is

One per cent of breast cancers occur in men, often later and with BRCA2 mutations; a firm lump under the nipple is the usual sign.

Symptoms & signs

  • Firm painless lump under the nipple
  • nipple turned in
  • discharge or bleeding
  • skin changes
  • swollen armpit nodes

🚩 Get help if…

  • see a doctor soon Firm lump under or near the nipple
  • see a doctor soon Nipple turning inwards or bleeding
  • see a doctor soon Sore or skin change on the chest that won't heal
  • see a doctor soon Lump in the armpit

Where it strikes

Medical treatment

  • Mammogram, ultrasound and biopsy
  • mastectomy with sentinel-node biopsy
  • tamoxifen (most are hormone-positive)
  • chemotherapy and radiotherapy as for women
  • genetic testing (BRCA2)
  • CDK4/6 inhibitors — palbociclib's licence extended to men (FDA 2019)

Natural & lifestyle

  • Know how the chest normally feels
  • healthy weight, less alcohol

Emerging & experimental

  • PARP inhibitors for BRCA carriers

Alternative, off-label & anecdotal

Approaches used outside the guidelines, with what their supporters report and what testing has found so far.

  • Exercise — lowers recurrence in women's breast cancer early / small studies
  • Soy — anecdotal in men anecdotal / traditional
  • Vitamin D — observational links early / small studies

ICD codes