Polycystic ovary syndrome
Syndroma ovariorum polycysticorum · Syndrom polycystických ovarií
female only
What it is
Insulin resistance and androgen excess disturb ovulation. Affects ~1 in 10 women.
Symptoms & signs
- Irregular or absent periods
- acne
- excess facial hair
- scalp hair thinning
- weight gain
- difficulty conceiving
🚩 Get help if…
- see a doctor soon No period for over 3 months
- see a doctor soon Fast new hair growth, a deepening voice or balding
- see a doctor soon Very heavy or very long bleeding
- see a doctor soon Great thirst and passing lots of urine
Where it strikes
- Ovaries
- Ovarian follicles
- Endocrine glands
Medical treatment
- Combined pill for cycle control
- metformin
- letrozole for ovulation
- spironolactone for hirsutism
- IVF if needed
Natural & lifestyle
- 5–10% weight loss restores ovulation in many
- low-glycaemic diet
- resistance exercise
- inositol 4 g/day (small trials)
- vitamin D
Emerging & experimental
- GLP-1 agonists
- inositol combinations
- AMH-targeted research
Alternative, off-label & anecdotal
Approaches used outside the guidelines, with what their supporters report and what testing has found so far.
- Spearmint tea — small trials lower testosterone and hair growth mixed evidence
- Berberine — trials show effects similar to metformin mixed evidence
- Acupuncture — trials disagree mixed evidence
- Cinnamon — small trials improve cycle regularity early / small studies
- Seed cycling — popular online; no evidence anecdotal / traditional
ICD codes
- ICD-10 E28.2
- ICD-11 5A80.1 Polycystic ovary syndrome