Sepsis
Sepsis · Sepse (otrava krve)
What it is
The immune response to infection turns on the body and organs start failing.
Symptoms & signs
- Fever or low temperature
- fast breathing
- confusion
- mottled skin
- low urine output
- extreme illness feeling
- low blood pressure
🚩 Get help if…
- call 112 / 911 now Confusion, slurred speech or very drowsy
- call 112 / 911 now Breathing very fast or gasping
- call 112 / 911 now Mottled, bluish or very pale skin, or a rash that does not fade
- call 112 / 911 now No urine for a day, or shivering with a fever
Where it strikes
- Blood
- Immune system
- Heart & arteries
Medical treatment
- Sepsis Six within one hour: oxygen, cultures, IV antibiotics, fluids, lactate, urine output
- source control
- vasopressors
- ICU
Natural & lifestyle
- Prevention: vaccination, wound care, prompt treatment of infections
- know the red flags
Emerging & experimental
- Biomarker-guided antibiotic duration
- cytokine haemoadsorption
- immunotherapy for immunoparalysis
Alternative, off-label & anecdotal
Approaches used outside the guidelines, with what their supporters report and what testing has found so far.
- Vitamin C, thiamine and hydrocortisone (Marik protocol) — large trials found no survival benefit not confirmed in trials
- Herbal antibiotics — no role; sepsis kills within hours without real antibiotics anecdotal / traditional
ICD codes
- ICD-10 A41.9
- ICD-11 1G40 Sepsis without septic shock