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Tuberculosis

Tuberculosis pulmonum · Tuberkulóza

What it is

A slow mycobacterium that walls itself into the lung; a quarter of humanity carries it latently.

Symptoms & signs

  • Cough over 3 weeks
  • coughing blood
  • night sweats
  • weight loss
  • fever
  • fatigue

🚩 Get help if…

  • call 112 / 911 now Coughing up more than a spoonful of blood
  • call 112 / 911 now Severe headache, stiff neck or confusion
  • see a doctor soon Cough over 3 weeks with fever, night sweats or weight loss
  • see a doctor soon Yellow skin or eyes, vomiting or blurred vision on TB drugs

Where it strikes

Medical treatment

  • 6-month RIPE regimen (rifampicin, isoniazid, pyrazinamide, ethambutol)
  • BPaLM for drug-resistant TB
  • directly observed therapy
  • contact tracing

Natural & lifestyle

  • Nutrition support — food parcels cut TB among household contacts in an Indian trial trials support
  • Vitamin D — no faster cure or fewer infections in trials not confirmed in trials
  • ventilation of living space
  • treat HIV and diabetes
  • BCG vaccination in children

Emerging & experimental

  • M72/AS01E vaccine (phase 3)
  • shorter 4-month regimens
  • host-directed therapy

Alternative, off-label & anecdotal

Approaches used outside the guidelines, with what their supporters report and what testing has found so far.

  • Vitamin D and sunlight — the sanatorium era used both; trials found no faster cure overall, possibly some benefit in certain genotypes mixed evidence
  • The sanatorium regimen — rest, fresh air, sun and rich food; it helped some before antibiotics and is no substitute for drugs anecdotal / traditional
  • Metformin as host-directed therapy — observational benefit; trials under way early / small studies
  • Garlic and curcumin — kill mycobacteria in the laboratory only early / small studies

ICD codes