Thyroid nodules & goitre
Nodus glandulae thyroideae et struma · Uzly štítné žlázy a struma
What it is
Lumps in the thyroid, found by ultrasound in up to two-thirds of adults and almost all benign; goitre — an enlarged gland — comes worldwide mostly from iodine deficiency.
Symptoms & signs
- Painless neck lump
- visible swelling of the neck
- pressure, swallowing or breathing difficulty with a large goitre
- overactive thyroid from a 'hot' nodule
- usually found incidentally
🚩 Get help if…
- call 112 / 911 now Noisy breathing or struggling to breathe
- see a doctor soon A lump growing fast over weeks
- see a doctor soon Hoarse voice for over 3 weeks
- see a doctor soon Hard lump with swollen glands in the neck
Where it strikes
Medical treatment
- Ultrasound risk scoring (TI-RADS) and fine-needle aspiration only of suspicious nodules trials support
- ultrasound follow-up of benign ones, less often over time
- radioactive iodine or surgery for overactive nodules
- surgery for pressure symptoms
- Levothyroxine suppression — abandoned: harm without benefit not confirmed in trials
Natural & lifestyle
- Iodine sufficiency (iodised salt)
- avoid unnecessary neck CT radiation
Emerging & experimental
- Molecular marker panels to avoid surgery
- radiofrequency ablation of benign nodules
Alternative, off-label & anecdotal
Approaches used outside the guidelines, with what their supporters report and what testing has found so far.
- Myo-inositol with selenium — small studies of smaller nodules early / small studies
- Iodine supplements to shrink nodules — can trigger hyperthyroidism; not advised anecdotal / traditional
ICD codes
- ICD-10 E04.9
- ICD-11 5A01.Z Nontoxic goitre, unspecified