Epidural space

Looks like

The space between the spinal dura and the bone and ligaments of the canal, filled with fat and a web of veins; in the skull there is none until bleeding creates one.

What it does

Cushions the cord and lets the spine bend; it is where an epidural anaesthetic or steroid injection is placed to numb nerve roots.

Keeping it well

An epidural abscess (fever, back pain, then weakness) or bleed can crush the cord and needs emergency surgery. In the skull, a torn artery after a blow to the temple makes an extradural haematoma — lucid, then rapidly unconscious.

Related conditions

• Acute liver failure
• ADHD
• African trypanosomiasis (sleeping sickness)
• Alcohol withdrawal and delirium tremens
• Altitude sickness
• Alzheimer's disease
• Amyloidosis (AL and ATTR)
• Autism spectrum disorder
• Bipolar disorder
• Birth asphyxia (hypoxic-ischaemic encephalopathy)
• Body dysmorphic disorder
• Bone metastases and spinal cord compression
• Botulism
• Brain abscess
• Brain aneurysm
• Brain tumour (glioma & meningioma)
• Cerebral palsy
• Chickenpox (varicella)
• Chronic insomnia
• Chronic neuropathic pain
• Chronic pain syndrome
• Cluster headache
• Concussion (mild TBI)
• Congenital hypothyroidism
• Cryptococcal meningitis
• Delirium
• Down syndrome (trisomy 21)
• Drowning
• Eating disorders
• Encephalitis
• Epilepsy
• Essential tremor & dystonia
• Fainting (syncope)
• Febrile seizures
• Fibromyalgia
• Fragile X syndrome
• Frailty & falls in older age
• Functional (somatic) symptom disorder
• Generalised anxiety disorder
• Guillain-Barré syndrome
• Haemorrhagic stroke
• Heat exhaustion & heatstroke
• Hepatic encephalopathy
• Huntington's disease
• Hydrocephalus
• Hypoglycaemia (low blood sugar)
• Intellectual disability
• Ischaemic stroke
• Japanese encephalitis
• Lead poisoning
• Long COVID (post-viral syndrome)
• Lyme disease
• Major depressive disorder
• ME/chronic fatigue syndrome
• Measles
• Medication-overuse headache
• Meningitis
• Migraine
• Multiple sclerosis
• Mumps
• Myasthenia gravis
• Narcolepsy
• Neonatal sepsis
• Neurocysticercosis
• Normal pressure hydrocephalus
• Parkinson's disease
• Peripheral neuropathy
• Phenylketonuria (PKU)
• Poisoning & overdose
• Post-traumatic stress disorder
• Postnatal depression
• Postpartum psychosis
• Rabies
• Restless legs syndrome
• Roseola (sixth disease)
• Schizophrenia
• Self-harm and suicidal crisis
• Shingles (herpes zoster)
• Spina bifida & neural tube defects
• Subdural haematoma
• Substance use disorder
• Tension-type headache
• Tetanus
• Thrombotic thrombocytopenic purpura (TTP)
• Tick-borne encephalitis
• Tics and Tourette syndrome
• Toxoplasmosis & CMV
• Transient ischaemic attack
• Traumatic brain injury (moderate to severe)
• Tuberous sclerosis complex
• Vascular dementia
• Vitamin B1, C and other deficiencies